SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '788ec46628f66f201b160eb4afc570cd8859454a436a7d166a2100c1e126b0e4' 
  AND token = 'dQ5rhCZ7VvhgT2PmYCa0CUZeX1WGB29ayYp0/bX54L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}