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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a64d78e3ab1816a98de72c1fe11776bcdd3faee0700df0f8aab1619952ccff66' 
  AND token = 'gY7wuBtJVRCH9XnEOnXzWF/eL24v0HybE1OtmDIWeOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}