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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb360f19a216c9389061122e3ff52f1b37d8e4b65c9f032c142163019b16bb8a' 
  AND token = 'AlebXOspZK+8lisZYseGfTQA5JWlGtkzISUdHYTCFu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}