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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff48b7eb91f3417131b9d58a739f2ca90ae3b7714630c93b1b4c9c5e9f0f35a' 
  AND token = 'GcP8O6/81I8IK+Mw8rJuW3kiAbdtZegX0SBjWdD0ET0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}