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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c984cc1e2b782608ed7e06b5152d2129c85b82be6f47570e279b694e6a0a0a' 
  AND token = 'ENc3lVskaCE+7F/zNbBeWixNvCmd+zC5bhsv3yTkUuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}