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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d3e69b4791cd02da76eb22810a384748d3eeebe88bf641e2520908f494f301' 
  AND token = 'CWKq+qU6Q5r5QMjWWyPQN9JFifBpV5XCnCCiLsT6mSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}