SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b25913fde2dcf84a555ee0976cc9e3fbe47b011f6f55b10b435379e0b8028a6' 
  AND token = 'rA92ZMdFTuUrbO/0WFQMR+U1anq4va4YDH6WZMZ7R7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}