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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a88197bd5ac5789c7b8bad1eddbd6e29c993122f54a195e3763c9af6322ca910' 
  AND token = 'qYKOHU3m7Ls6LUNWmIEStrVM0ekmxMx09uRPPt8eOWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}