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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d1e269e6bd5e1f33fffbf1e7acb1864f742bf7828663c4cd21dad01521db95' 
  AND token = 'X1FO1qA8IwqaRME5hEryn26IhmDRw5n0bD84EtYdYPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}