SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10332526cf24c9bebd39a5d5c7e0ace7e3d75d3d2e43fe1172a3cbfa3a8b0f97' 
  AND token = 'kbNKz5YtKFvbUWHMdMf2b2uHQVz1ZZrAMuo3FBw0flM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}