SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad9ce621391884fabee6f7a9f333a5b723e1614097ef499b964f97aa84af5718' 
  AND token = 'CatwKm/Q4GPcREHcfaV/BnPf/FZ5E4qhxcfMUsywMPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}