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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c2c1ca7929599a95635afc12f370ad18ee11eb6c7ba7fb56be262fc52fa7a2c' 
  AND token = 'xa+ldr65fEXHSAa1cDSxbmbZ/vXVUs2EXxc2MCnaSRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}