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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c610e47ffe4023f4bbda3edf2a57a71eddc114f640b1dfa25aa28c77774562' 
  AND token = 'T58T69O4PJXknTaj5K6SfiLG/nsEQt1Bhszi1NLOFNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}