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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5bbb8b21bb67d214338bc17ea4afe8942efb29fe96c74ab8f1bd85a9e33f3db' 
  AND token = '3EWbvVpUSNbbZq6eSbzmH4Ece/Ai9IB9UqHb/0/vnKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}