SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a18162123500ba9388251427e1954acf40193e295042a75a1c263c47a2cb8cea' 
  AND token = 'P4jHbbwO1b3GsCZgaxRQg9v1hkoUZBkMllPxoCmud+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}