SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '798d7b5d89a31f594e4817067121e7446e8a10e2ea5e21b0e4ab29509b817a33' 
  AND token = 'OWAPIFEtrZXtaEaQDU0doJgTC7KEv4nPnPk5h3Ggw/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}