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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb17739a1015888ce213a10ee34458c157af396c63bf6e65322b8a22b773fcc' 
  AND token = 'StuxxCQ21ZS+AxJVE2mOp1puYJbgMRDPO6N96ZFxcGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}