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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79145caf1a42ffabbd871831f7274ec1b08d4ff989a12dc7b11a4382cc71c5be' 
  AND token = 'ls0kbFWuc5PhjG0mfAeWrTG0U6lyvuM726uCIz2kxp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}