SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dfdbd88cbf8bf7eb12173b8253523d003be6556a199b14ce2ad614b5b35765d' 
  AND token = 'WywlZWlIHbpWIxbv2l8+RknGvsr1xepe8jdiZ0IQb1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}