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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7eaff4b2b0614ec227d1ef9674378c69e4715996f649ac6c5a318566009d24' 
  AND token = 'dR0WmFE2V6vyqttzFWoBsGCJy6Wf6vwnRNMbTT67U/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}