SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781dd114fe997599326e8b0a3151782029a1027191d28798a3f5bca59c1c121a' 
  AND token = '83kOOpnGMsz13PV70qEAod9oUz48j6mSVbZYjveKfqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}