SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3806c385d5bb338a08fb8ec023c7fc43ad15b620663a79b07b430f22f09d275' 
  AND token = '/uowqCumKea6RBQGFS5NVWKxBa2OqnRb/xCAsf11HAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}