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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '071d3646fe16ec6e36019fa87d0aa7bd7f721e831fe977142a78040bf5098304' 
  AND token = 'fOTe9vEppCnM3zGAvNCqstE0UEpmiiQ7Epkw3H6tpBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}