SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2577213e19ab785163225ddbbd55e4d9d25b947bf2589f91613f4c5adc1e229d' 
  AND token = 'lW5RBj7H3+iCynSH2jYdL+NTMFtvA///m74GnFy0eIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}