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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e51108fc7be02290225fa1d316b8c0c3041fe4f70bc0c2dbea1e63987c50948f' 
  AND token = '9YHeyd0ynkI19OhtztNo1He3QaTErYHfq+OuzgpeKgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}