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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e554210e4888d1c0192659afb59c97035a55369ed01680f3fba61386df29f118' 
  AND token = '3es1oja8IbYlHilkvOXOX5FzZ7HYjb8ku9Gt8L00bLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}