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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d4df7c74defc1ef570eef595f20af402208c1e0c4135382e84d70d7703ae050' 
  AND token = 'IJMFu9qMFbkDolGsQMDcT+eLFAYdheT3bMYyVO0Fffs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}