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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '942e5813ef920b6b9c7ce30ba9c7acbb105354497e4205d55e1761c79ae4e1c1' 
  AND token = 'cqAAnoI5hmqRc+JEKRWRUU3UPpaGso5rpA6Y6QfQcug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}