SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ab95bdd5d125d16d5af6bc9ddbc96a09f5cae85051f1fce393347b048755ac2' 
  AND token = 'JFzV5mINZOAB3gnNuMDBRjhciTAR4nH61acBlDnWxL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}