SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49aa5fe113b67189bc8d90375ef28a5be56bdcf7667307248204e14a84e4aa5' 
  AND token = 'wIscFwtRAE/VfVTZmIS6BEroIsQzEgNIeCAQ5zJnFD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}