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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4e45f82e7030c6ae4835fb6b0157f3b4aa488703b15f25a6b05213e19fe144c' 
  AND token = 'DPy6uKiVbQBWF0jKaaSH5nO9k9wTF/5NFhoGWryf5ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}