SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '234356713bc062595944c7b93b5299b88e05429243a0b0644c509e8799a1a159' 
  AND token = 'Df7e/3ojuTuFU7UAKOWFan00PAdG44FIJ+hkCqwynbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}