SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a1fd3a6addf71839d0f22cefef153b4bb312e8acd9310b1b9d078aa648e544' 
  AND token = 'ES57zi8WQgiff9CvaloG7ccMWa2Yjml+kH6cG6EBeJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}