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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35ff159b2c685690fa376c4f7d1c3e73c3e4d692e52ce8db91e71dd34d7efefc' 
  AND token = 'NGZeZB6mhNV6EwoG0VBMDh8a9qrTqK7/h5W/9gin1XM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}