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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89dfa7e21c4106edebb285e8f59cc429610cc301e01c93fad252d37f54d3a199' 
  AND token = 'pDQp5I8qpS5+fc2a5XOKrIfM39lKlAe2Ewrv3LjK5nQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}