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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ba8ad9befa51a6647ca358b371d0c27f6e43be7182e3ecdf1995d0ca1750d7d' 
  AND token = 'kVD6DJwCQfxLhdE/HQq/X1kHs0QAMpPiO1IQ9hnrSm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}