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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45dcb835056738f937a37842a3034d1a4fadca44f272d7bdf033c325ad5a3c70' 
  AND token = 'NZdXh7AGBFdUuyGk0SbJTHZmCT3mTJgCdS8j19MSFs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}