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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94ad7f446a9817035a4409dbd97ec0b6bcdddd51b1f797da7abcf39a895aa881' 
  AND token = 'azf/hYxZAdf3JgaGOdJ+OhwrCuMN94ynyA35+9Y3Vf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}