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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf468f268f113c41ce609c5679b9a2489fd495cfdbfcc0ff228a39eff98e8840' 
  AND token = 'ceXtIGVokb3irx60+d60DNmKPRjV02+V8vbi6LYASZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}