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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e81c4feb335fdb0c4cb4478e76ad1e9da4d94fb820ce0323bda3c48462140809' 
  AND token = 'IiT/qb7ysBGOWWPgau8WO93lKcmK1CvCLL/RdI92V1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}