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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e7f3cd169e8dfa5477e6f61ab18d9ad0a8fac320de1032a2336835e00ddea2' 
  AND token = '0Q9RiTuMVSYUJCjU1ODMDgqeRw+hFAAvcaCDQf3M3uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}