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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0416f2336669d3b6b5303f68f645ad71ef79ba3817c7cf741e2ee1c4437f961' 
  AND token = 'Plbj+JER+6UQ3oKvq0KkEL39LWUaoU71hilVoclve7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}