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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78d852e75714c62d2754fa1c2f68a3d7585f8d3fd1393feeda57607bee923cc' 
  AND token = '1OrchXQBFmDunspfALXzY3PC8Bas+gH9fEQY4bRNThQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}