SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ec18b1cd65f713de6521836d3c9e5f12346e60c2d5877e2ed5c24e1419a620' 
  AND token = 'hR0G+Nzi57b6BxveOAvu9GdCQiAFgJt/LdoknkRgazs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}