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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b87484f6de870b8b0431605582596a3ce8bc17f922919a50db117218388eb1b' 
  AND token = '6H5H+w3ZCGdaTXoWkRzvaVeXVaL9BSAy2v3YGuTMCBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}