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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4656ec707d6f6dc042c40d6028ef04b13e883b7ad336ccff77960a251da1f6fb' 
  AND token = 'jmPYtAn91NL3nuzACeaXU0BBMN6nmp8nRUqWNMn8mUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}