SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88020e9c51c055be248f5fc6766d3edbb849e4fdc9ee9ad3460787c69053bcc3' 
  AND token = 'eS13Qhkom5lTdF5PQXmqI44o9KJYQdRs5xpl+AnZtqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}