SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b6da55da1d596aa5a41b6033279f062085aa3c7e242844ac757a1bc8a0b0ce' 
  AND token = 'XQAzbPWcVnkvZc8vzn4qrd5yZ85L7RrJ69eQDlUTjRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}