SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d380ed8f8589e6b401da40b5b7564a01b1748e17d200b37b4ff69fbfa9923e' 
  AND token = 'Irqp84++cgwInuMTfbhdUKfgLvA3Yh+b409jMJyfeaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}