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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '368621528423a8a6d7c950bab926b6bef53919186d9aa6a184056781bc03e0d5' 
  AND token = '6B0r4nfuVGdsVWlBzu5rEJKScmhVSUVmW33ro1nUw6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}